Phospho eif4b
Polyclonal Antibody for studying eIF4B (Ser422) phosphate. Cited in 46 publications. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho-eIF4B (Ser422) Antibody (CST #3591) is ready to ship. WebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins …
Phospho eif4b
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WebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins are EIF4A, EIF4F. eIF4B is involved in translation of numerous proliferative or anti-apoptotic mRNAs with highly structured 5'UTR and subsequently affect cell growth … WebPhospho-eIF4B (Ser406) Antibody detects endogenous levels of eIF4B protein only when phosphorylated at Ser406. Species Reactivity: Human, Mouse. Species predicted to react …
WebApr 6, 2024 · The protein expression of mTOR, phospho-mTOR, p70 S6 kinase (p70 S6K), phospho-p70 S6K, eIF4B, phospho-eIF4B, eIF4G, 4E-BP1, phospho-4E-BP1, eIF4E, phospho-eIF4E, and Rpb1 in the liver was assessed using western blotting. Actin was used as the loading control. (Specific antibody information is provided in the Supplementary Materials.) WebProduct Details Target Information The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP.
WebSep 5, 2024 · eIF4B phosphorylation patterns in hippocampal neurons and cortical astrocytes. ( A) Western blot analysis of total cell extracts from neurons or astrocytes … WebNov 18, 2016 · The activity of eIF4B is modulated by phosphorylation, which is mediated by two major signaling pathways, the MEK1/2-ERK1/2-RSK pathway and the PI3K-Akt-mTORC1-S6K pathway [8], [9], [11], [12]. Overexpression or depletion of eIF4B affects cell survival and proliferation [13], [14].
WebPhospho-eIF4E (Ser209) Antibody detects endogenous levels of eIF4E only when phosphorylated at serine 209. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser209 of human eIF4E.
WebProduct Details Target Information The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. how to make old-fashioned homemade root beerWebAnti-eIF4B (phospho S422) antibody See all eIF4B primary antibodies Description Rabbit polyclonal to eIF4B (phospho S422) Host species Rabbit Tested applications Suitable for: IHC-P, WB, ICC/IF more details Species reactivity Reacts with: Mouse, Human Immunogen Synthetic peptide corresponding to Human eIF4B aa 350-450 (phospho S422). T-G-SP-E-S mt baker veterinary clinicWebPhospho-EIF4B-S422 Rabbit pAb (AP0278) Datasheet SDS Tested applications: WB IHC Reactivity: Human, Mouse Western blot analysis of extracts from HeLa cells using phospho-EIF4B-S422 antibody (AP0278). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. mt baker snow packWebHuman Phospho-eIF4B (S422) Antibody Summary Species Reactivity Human Specificity Detects human eIF4B when phosphorylated at S422 Source Monoclonal Rat IgG 2A Clone # 866049 Purification Protein A or G purified from hybridoma culture supernatant Immunogen Phosphopeptide containing the human eIF4B S422 site Formulation mt baker vacation homesWebAll lanes : Anti-eIF4B (phospho S504) antibody [EP2261Y] (ab75823) at 1/50000 dilution Lane 1 : 293T cell lysate, untreated Lane 2 : 293T cell lysate, treated with AP … how to make old fashioned oats in microwaveWebPhospho-EIF4B (Ser406) EIF4B (Eukaryotic Translation Initiation Factor 4B) is a Protein Coding gene. Among its related pathways are Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include nucleic acid binding ... mt baker vineyards wineryWebJan 9, 2012 · The lower lane shows tubular cell expression of actin under similar conditions. A bar diagram shows cumulative data of four sets of experiments in the right panel. B. Representative gels (in duplicate) showing tubular cell expression of phospho-eIF4B under control (vector) and HIV infection states (upper lane). how to make old fashioned marshmallow candy