WebSecondary outcomes included responses at 7 and 30 days after the initiation of granulocyte therapy, and post-transfusion ANC, stratified by HLA alloimmunization status. Accurate post-transfusion white blood cell (WBC) increments were reliably obtained for the first 10 patients; this information was calculated from a complete blood count ... WebOct 29, 2015 · A total of only 114 subjects were enrolled (56 assigned to the granulocyte transfusion group and 58 to the control group). Transfused subjects received a median …
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WebGranulocyte transfusions have been used since the 1960s with varying degrees of clinical success in the treatment of infection in patients with neutropenia or inherited granulocyte disorders. A number of studies have indicated that efficacy may well be associated with the dose of granulocytes delivered. Collection of granulocytes using modern apheresis … WebAug 5, 2013 · Traditional granulocyte transfusion therapy, a logical approach in treating these infections, has been available for many years, and several controlled studies have shown this therapy to be useful. However, granulocyte transfusion therapy fell out of favor because the results were not clinically impressive, and adverse results were … inclusive finance india awards
Granulocyte transfusions made with modified fluid gelatin in …
WebJan 15, 2001 · The clinical utility of granulocyte transfusion therapy remains controversial. In 1995, Strauss analyzed 32 studies that reported the outcome of granulocyte … In a 1934 experiment, Strumia gave neutropenic patients intramuscular injections of neutrophils, but this proved ineffective in improving their neutrophil function. In 1953, Brecher et al. demonstrated the principle behind granulocyte transfusion by infusing neutrophils into dogs and showing that they travelled to sites of inflammation. The first human granulocyte transfusions were carried out in the 1960s, using white blood cells harvested from people with chronic myeloid leu… WebGranulocyte transfusion therapy (GTX) is considered as a logical therapeutic approach for these problems. However, the efficacy and complications of GTX have not been well identified. We retrospectively analyzed the clinical outcomes of GTX therapy in our hospital from 2009 to 2015. After 117 granulocyte transfusions for 47 patients, 72.3% of ... inclusive finance for development