WebEstrogen receptor (ER) α is expressed in the vast majority of breast cancers and is one of the most successfully prosecuted drug targets in oncology, with multiple classes of … 三核苷酸重复序列扩增(英語:Trinucleotide repeat expansion, Triplet repeat expansion),也称三核酸重复序列扩增、三核苷酸重复扩增、三核苷酸扩增等,是一种可能导致三核苷酸重复序列疾病(英语:trinucleotide repeat disorder)的DNA突变。在动态遗传学(英语:dynamical genetics)中被称为动态突变(英语:dynamic mutation)。 在DNA复制中,三核苷酸重复序列扩增由DNA复制时的滑动现象(英語:slippage) 造成 。DN…
Comparison between static and dynamic mutations
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Mutational dynamics of early and late relapsed childhood ALL: …
In genetics, a dynamic mutation is an unstable heritable element where the probability of expression of a mutant phenotype is a function of the number of copies of the mutation. That is, the replication product (progeny) of a dynamic mutation has a different likelihood of mutation than its … See more • Most of these diseases have neurological symptoms. • Anticipation/The Sherman paradox refers to progressively earlier or more severe expression of the disease in more recent generations. See more • Fragile X syndromes • Huntington's disease • Myotonic dystrophy See more Web动态突变" 英文对照 dynamic mutation; 动态突变是指DNA中的碱基重复序列拷贝数发生扩增而导致的突变.在动态突变中的重复单位片段的大小从3个碱基到33个碱基长不等。 WebOct 1, 2005 · Repeat instability is a dynamic mutation and is defined by both cis -elements and trans -factors. Both germline (parent-to-offspring) and tissue-specific somatic instability occurs. There are ... sample reflections of a mentor for a funeral